Bacterial ID and Susceptibility Microfluidic Cartridge

Our Role

  • Design an instrument driven cartridge which performs an assay of sample division, capture, imaging and processing of several reagents in order to identify bacteria and measure reaction to antibiotics.

Project

  • IVD
  • Point of Care
  • Cell Culture Equipment

Client

Accelr8

Features & Accomplishments

  • Developed a method to divide sample into 8 equal volumes. Building on the success, developed a method to divide sample into 64 equal volumes.
  • Designed and prototyped fluidic channels that are 400 μm wide.
  • Integrated injection molded components with multiple laminate structures in a unique design.
  • Developed a heat seal method to assemble the laminate structures with the injection molded cartridge body.
  • Developed unique valve that is actuated within the laminate structure using compressed air.
  • Designed cartridge to accept mechanical inputs from an instrument in order to complete the assay.